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Pharmacogenetics studies our predisposition to drugs. Thanks to this DNA analysis, we can determine the predisposition that a drug may be toxic to us or simply ineffective.
Find out your genetic predisposition to drugs with a DNA analysis!
We have always observed how some medicines have the desired effect in some people, but not in others. There may be many causes for these differences, and pharmacogenetics is undoubtedly one of the most important factors.
Our pharmacogenetics DNA analysis looks at a list of drugs. We are based on recognized scientific studies to which we apply your genetic data. By checking your genetic data with these studies, our algorithms show us your predisposition to these drugs.
Download our sample Pharmacogenetics report
Reports available in English, German, French, Italian, Polish, and Spanish.
Pharmacogenetics and pharmacogenomics: is it the same?
Pharmacogenetics and pharmacogenomics are words that are often used synonymously, but have some differences. Pharmacogenetics is the biological discipline that studies a person's genetics in response to medicationsWhile pharmacogenomics studies the variation in the expression of genes relevant to diseases and the variable response to certain drugs to develop new avenues of treatment.
How can a Pharma DNA Analysis help me?
Currently, adverse drug reactions lead to significant morbidity and mortality in patients, which in many cases leads to increased health costs. While drug compatibility has been known and studied for many decades and any leaflet specifies the incompatibility of a drug with many others, genetics also have a lot to contribute. To assume that patients are a homogeneous group of people and that the drugs and treatments that are usually effective in one group of individuals will be so in the rest, is almost certainly a wrong approach. Clinical experience shows that drugs that work very well in some patients, have many side effects, are ineffective, or cause adverse, even fatal, effects in others.
The lack of efficacy in treatments for genetic disorders such as Alzheimer's, schizophrenia or hypertension rises to very high percentages.
Variations in response to medications may be due to exogenous factors. For example, diet, consumption of coffee, tobacco, alcohol, other medications, etc. Pero also endogenous factors, such as age, sex and, very importantly, genetics.
A drug can be administered by different routes, which will influence the speed of its effects, but, in any case, it goes through a multitude of stages before reaching the tissue or organ for which it is indicated. It must be absorbed, metabolized, transported, degraded and excreted. In any of these steps, a variation in the sequence of a gene can interact with the drug and generate a different response than expected.
Thanks to DNA pharmacogenetic analysis we can know our predisposition to various drugs.
In such a way that doctors can avoid those that we know that it is very possible that they cause us toxicity or that they simply will not have the desired effect. Physicians can choose the most effective drugs according to our genetics and calculate the doses in a much more intelligent way.
The Netherlands has been using the genetic information of its patients for years, who carry this data on their health card, so that the drugs are modulated in the pharmacy based on this personalized information.
Personalized medicine, which is also called individualized medicine o genomic medicineit's one in which doctors try to prevent, diagnose or treat a genetic disease, depending on its stage, using the genetic or biological information of a patient and that becomes, at the same time, a fundamental element for saving costs (and time) in health systems, because the trial-error system is consistently reduced. Prevention medicine is also talked about, when the criterion is more the moment of evolution of the disease; in this case, before developing it.
There are medications that, once prescribed, take months to be evaluated, to know if they are having the desired effect or not. In many cases, for the same pathology there are different pharmacological alternatives, and our doctor, having our pharmacological report, you will have a better chance of getting it right "first time".
Our Pharmacogenetic DNA Analysis is divided into 5 specialties medical: cardiology, neurology, pain, oncology and others. Y analyzes predispositions to dozens of drugs.
These are some of the drugs we analyze
Cardiology - Phenprocoumon
Neurology - Amisulpride
Cardiology - Hydrochlorothiazide
Cardiology - Warfarin
Neurology - Amitriptyline
Cardiology - Pravastatin
Neurology - Antidepressants
Pain - Aspirin
Neurology - Bupropion
Pain - Fentanyl
Neurology - Carbamazepine
Neurology - Citalopram
Pain - Buprenorphine
Neurology - Clomipramine
Pain - Alfetanil
Neurology - Clozapine
Pain - Meperidine
Neurology - Escitalopram
Pain - Morphine
Neurology - Haloperidol
Pain - Naltrexone
Neurology - Olanzapine
Pain - Pentazocine
Neurology - Paliperidone
Pain - Tramadol
Neurology - Quetiapine
Oncology - Fluorouracil, Capecitabine, Pyrimidine Analogs
Neurology - Ziprasidone
Oncology - Cisplatin
Neurology - Risperidone
Oncology - Irinotecan
Others - Ribavirin
Oncology - Mercaptopurine
Others - Interferon alfa - 2b
Oncology - Methotrexate
Others - Tacrolimus
Oncology - Tamoxifen
Others - Viagra (Sildenfail)
Oncology - Vincristine